Anti-JCV antibody index does not change during ocrelizumab-treatment
نویسندگان
چکیده
منابع مشابه
Longitudinal analyses of anti-JCV antibody index for risk assessment of progressive multifocal leukoencephalopathy
Risk assessment for natalizumab-associated progressive multifocal leukoencephalopathy (Nat-PML) comprises the anti-JC virus (JCV) antibody index (AI). The anti-JCV AI was longitudinally determined in a natalizumab-treated MS cohort (Nat-MS, n = 468) and samples of Nat-PML patients (n = 15). In Nat-MS, the median AI was 0.8 (25th to 75th percentile, 0.2-2.8) with an intra-individual coefficient ...
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Background: Early diagnosis of appendicitis is important during pregnancy. Unlike omentom, cecum and appendix are not likely to be displaced by the growing uterus, so the concept of position change of the appendix during pregnancy is questionable. Objective: To determine the anatomical location of appendix during pregnancy. Methods: In a prospective study from October 1995 to March 1999, 291 w...
متن کاملRising JCV-Ab index during natalizumab therapy for MS
Infection with JC virus (JCV) is not noticeable and is usually inconsequential. Natalizumab therapy, however, blocks the very late antigen-4 adhesion molecule on immune cells, preventing them from attaching to vascular cell adhesion molecule-1 on brain endothelial cells and then penetrating into the CNS. The dearth of T cells, and perhaps other factors, allows JCV to infect oligodendroglia and ...
متن کاملStability and predictive value of anti-JCV antibody index in multiple sclerosis: A 6-year longitudinal study
BACKGROUND Risk of natalizumab-related progressive multifocal leukoencephalopathy is associated with the presence of anti-JC-virus (JCV) antibodies. OBJECTIVE To investigate the longitudinal evolution of anti-JCV antibody index and to determine the predictive value of baseline anti-JCV antibody index for long-term stability of anti-JCV antibody status. METHODS MS patients from the MS centre...
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where d is the distance between the center of masses of the two symmetrical halves of the CSAs. Critical to the use of this theorem is the determination of the exact center of mass of each CSA (6, 7). The authors did not specify how the center of mass was determined nor the accuracy, precision, and variation of this measurement in the bovine lens. There are additional significant deficiencies w...
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ژورنال
عنوان ژورنال: Multiple Sclerosis Journal - Experimental, Translational and Clinical
سال: 2020
ISSN: 2055-2173,2055-2173
DOI: 10.1177/2055217320960510